One of the most important Democratic donors in the past two decades, whose generous contributions helped pay for the DNC headquarters in Washington, D.C., has indicated that he will not contribute to President Obama’s reelection campaign in 2012, because of the administration’s stance on Israel.

Billionaire financier Haim Saban told CNBC last night that Obama hasn’t done enough to show support for Israel. He also said that he has no plans to contribute to the president’s campaign.

“President Obama has raised so much money and will raise so much money through the Internet, more than anybody before him. And he frankly doesn’t, I believe, need any of my donations,” said Saban.

“I’m very perplexed as to why the president, who’s been to Cairo, to Saudi Arabia, to Turkey, has not made a stop in Israel and spoken to the Israeli people,” he continued. “I believe that the president can clarify to the Israeli people what his positions are on Israel and calm them down. Because they are not calm right now.”

There have been reports that Obama is losing Jewish support after his clash with Prime Minister Netanyahu last week, but this development is the most significant so far. If a key donor like Saban has decided to break with the president, then there are likely others who will follow suit.

Steve Rosen, director of the Washington office of the Middle East Forum, and a former AIPAC official, said that this is part of a trend of Democrats rejecting Obama’s policy toward Israel.

“It’s not happening in isolation. It’s happening in a context in which Harry Reid broke with the president in the last two days,” Rosen told me. “I think that Saban is another step in that direction.”

Saban told CNBC that he will continue to enlist others to contribute to Democratic candidates. The DNC, which has received millions from Saban over the years, hasn’t yet replied to a request for comment.

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